Zycortal For Dogs Side Effects

Refer to the prescribing information for complete details.

Zycortal for dogs side effects.

Like other adrenocortical hormones percorten v may cause severe side effects if dosage is too high or prolonged. Zycortal suspension replaces mineralocorticoids which are deficient in dogs with addison s. Zycortal suspension should be used with caution in dogs with congestive heart disease edema severe renal disease or primary hepatic failure. Both groups were administered an initial dose of 2 2 mg kg.

One hundred thirteen 113 dogs were treated with zycortal suspension and 39 dogs were treated with the active control. Zycortal is a new treatment for addison s disease hypoadrenocorticism in dogs. It is given by injection at approximately 1 month intervals. The precise dose and frequency is calculated by your vet in response to blood test results and clinical assessments made durong the initial phases of treatment.

Possible side effects of zycortal suspension include polyuria excessive urination polydipsia excessive thirst increased blood volume edema and cardiac enlargement. Reduce dosage in dogs showing signs of hypernatremia or hypokalemia. The most common side effects with zycortal which may affect more than 1 in 10 dogs are polydipsia increase in water intake and polyuria increase in urine production. For the full list of all side effects reported with zycortal see the package leaflet.

Do not use in pregnant dogs or in dogs suffering from congestive heart failure severe renal disease or edema. Both groups were administered an initial dose of 2 2 mg kg. Subsequent doses administered and or frequency. In a laboratory study zycortal suspension was administered via subcutaneous injection to 32 beagle dogs four groups of 8 dogs each at doses of 0 1 3 and 5 times the labeled starting dose 1x 2 2 mg kg once every 21 days for 6 months for a total of 9 injections.

One hundred fifty two 152 dogs of various breeds 0 5 12 4 years of age and weighing 2 1 134 6 lbs 0 95 61 2 kg were enrolled. Excessive weight gain may indicate fluid retention secondary to sodium retention. Some patients are more sensitive to the actions of zycortal suspension and may exhibit side effects in an exaggerated degree. Do not use in pregnant dogs or in dogs suffering from congestive heart disease severe renal disease or edema.

Dogs presenting in addisonian crisis must be rehydrated with appropriate intravenous therapy before starting treatment with zycortal suspension.